Robert Beitle
Professor
Louis Owen Professorship in Green Chemical Process Design and Development
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Professor Beitle joined the faculty in 1993 after completing his Ph.D. in chemical engineering at the University of Pittsburgh. His principal area of expertise is biochemical engineering, with an emphasis on bioseparation and fermentation. Dr. Beitle advises students in two graduate degree programs: chemical engineering, and cell and molecular biology. He currently is a member of the Executive Committee of the Biochemical Technology Division of the American Chemical Society, and is an active member of the American Institute of Chemical Engineers.
Education
MS, Chemical Engineering, University of Pittsburgh, 1991
BS, Chemical Engineering, University of Pittsburgh, 1987
Selected Publications
Patent
Microvolume Immunoabsorbant Assays with Amplified Electrochemical Detection. US Patent #6,887,714.
Peer Reviewed Publications
* = Shows greater than ten citations via ISI. # = Shows greater than twenty citations via ISI.
Beitle, R.R., Ataai, M.M. The purification of TEM-β-lactamase From Cell Extract Using Immobilized Copper Affinity Chromatography. Biotechnology Techniques 5 (1991) 107.
Beitle, R.R., Ataai, M.M. A Unique Monitoring and Control System For Laboratory Fermenters. Biotechnology Techniques 5 (1991) 77.
Sagar, S.L., Beitle, R.R., Ataai, M.M., Domach, M.M. Metal-Based Affinity Separation of α- and γ-Chymotrypsin. Bioseparations 3 (1992) 291.
Beitle, R.R., Ataai, M.M. Immobilized Metal Affinity Chromatography and Related Techniques. In New Developments in Bioseparation. AIChE Symposium #88 (1992).
*Beitle, R.R., Ataai, M.M. One Step Purification to Homogeneity of a Model Protein from Periplasmic Inclusion Bodies by its Fusion to an Effective Metal-Binding Peptide. Biotechnol. Prog. 9 (1993) 64.
Beitle, R.R, Ataai, M.M. Advanced Data Acquisition for Fermentation Experiments. Process Control and Quality 4 (1993) 99.
#Hoefling, T.A., Beitle, R.R., Enick, R.M., Beckman, E.J. Design and Synthesis of Highly CO2-Soluble Surfactants and Chelating Agents, Fluid Phase Equilibria 83 (1993) 203.
#Newman, D., Hoefling, T., Beitle, R., Beckman, E.J. Phase behavior of fluoroether-functional amphiphiles in supercritical carbon dioxide. J. Supercritical Fluids 64 (1993) 205.
Ataai, M.M., Beitle, R.R. Use of Divalent Metal Ions Chelated to Sepharose and Agarose Derivitives for Reversible Protein Immobilization. In: Methods in Molecular Biotechnology: Immobilization of Enzymes and Cells #1 (1996).
Chai, S.A., Beitle, R.R., Coleman, M.R. Facilitated Transport Metal Affinity Membranes. Int. J. Biochromatography 2 (1996) 125.
Subramaniyan, A., Sublette, K., Beitle, R. Microbial Oxidation of Mixtures of Methylmercaptan and Hydrogen Sulfide. Applied Biochemistry and Biotechnology 70 (1998) 995.
*Abudiab, T.A., Beitle, R.R. Preparation and Use of Magnetic Immobilized Metal Affininty Separation Media for Protein Isolation. J. Chromatography A 795 (1998) 211.
Morrow, J., Crawford, J., Beitle, R. Characterization and Modeling of Membrane Chromatography When Different Spacing Elements Are Employed. In: Advances in Filtration and Separation Technology Volume 13 (1999) 575.
J. Crawford, S. Ramakrishnan, S. Gardner, M. Coleman, R. Beitle. Immobilized Metal Affinity Membrane Chromatography: Characteristics of Two Materials of Differing Preparation Chemistries. Separation Science and Technology 34 (1999) 2793.
Taylor, A., Oxford, C., Crookston, D., Beitle, R.R., Coleman, M.R. Effect of Chelated Metal on Amino Acid Transport in Facilitated Transport Membranes Incorporating Metal Affinity. In: ACS Symposium 744 on Membrane Formation and Modification (2000) 238.
Nutt, M., Crookston, D., Beitle, R. Supported Poly(Vinyl Alcohol) Hydrogels for Facilitated Transport of Histidine. Separation Science and Technology 35 (2000) 785.
Conner, J., Beitle, R., Duncan, K., Kolhatkar, R., Sublette, K. Biotreatment of Refinery Spent Sulfidic Caustic Using an Enrichment Culture Immobilized in a Novel Support Matrix. Applied Biochemistry and Biotechnology 84 (2000) 707.
*Li, Y., Agarwal, A., Sakon, J., Beitle, R. Characterization of Metal Affinity of Green Fluorescent Protein and Its Purification via Salt Promoted, Immobilized Metal Affinity Chromatography. J. Chromatography A 909 (2001) 183.
Teo, J., Beitle, R. Novel Solvent Stable Micro-porous Membrane Made of Whey Protein Isolate Gel. Journal of Membrane Science 192 (2001) 71.
Dunkan, K., Sublette, K., Rider, P., Stepp, A., Beitle, R., Conner, J., Kolhatkar, R. Analysis of a Microbial Community Oxidizing Inorganic Sulfide and Mercaptans. Biotechnology Progress 17 (2001) 768.
Yi, L., Beitle, R. Protein purification via Aqueous Two-Phase Extraction (ATPE) and Immobilized Metal Affinity Chromatography. Effectiveness of salt addition to enhance selectivity and yield of GFPuv. Biotechnology Progress 18 (2002) 1504.
Teo, J., Beitle, R. Preparation of Whey Protein Membranes for Industrial Application, Fluid/Particle Journal 15 (2003) 61.
Wallace, S., Carrier, J., Beitle, R., Clausen, E., Griffis, C. HPLC-UV and LC-MS-MS Characterization of Silymarin in Milk Thistle Seeds and Corresponding Products. J. Nutraceuticals, Functional and Medicinal Foods 4 (2003) 37.
Cai, Y., Moore, M., Goforth, R., Henry, R., Beitle, R. Genomic data for alternate production strategies I. Identification of major contaminating species for Cobalt+2 Immobilized Metal Affinity Chromatography. Biotechnology and Bioengineering 88 (2004) 77.
Teo, J., Song, L., Beitle, R. Microporous whey protein isolate gel adsorbent. Separation Science and Technology 40 (2005) 991.
Lau, C., Carrier, J., Beitle, R., Howard, L., Lay, J., Liyanage, R., Clausen, E. A Glycoside Flavonoid in Kudzu (Pueraria lobata) Identification, Quantification, and Determination of Antioxidant Activity. Applied Biochemistry and Biotechnology 121–124 (2005) 783.